Researchers are continuing to find strong evidence linking asthma to the risk of cardiovascular disease and events like heart attack and stroke. In a 2015 study conducted at multiple university medical centers in the U.S., researchers found that adult men and women with persistent asthma had a significantly higher risk for cardiovascular disease than non-asthmatics. The researchers characterized persistent asthmatics as those using controller medications, including inhalers and oral steroids.
The findings were based on analyzing medical information in a long-term multi-ethnic study of arterial disease. The database included nearly 6,800 subjects: 53% women, 28% African-American, 22% Hispanic, and 2% Asian-American. Among them were 156 persistent asthmatics.
Over a nearly 10-year period, the group of medication-controlled asthmatics was found to have a 60 percent higher rate of cardiovascular events than non-asthmatics.
The researchers noted that the individuals with persistent asthma had higher levels of C reactive protein, a protein released into the blood in the presence of active inflammation in the body, as well as fibrinogen, a protein that promotes blood clotting. Elevation of both proteins has been linked to cardiovascular disease.
Reference:
- Tattersall MC, et al. Asthma Predicts Cardiovascular Disease Events. Arterioscler Thromb Vasc Biol. 2015;35:1520-1525.
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