Dr. Sinatra's HeartMD Institute

Brain Stent Study Ends Abruptly

stenting vs. risk factor management

On Sept. 7, 2011, researchers pulled the plug on a randomized trial designed to compare treatments for an extremely common cause of stroke: atherosclerotic intracranial arterial stenosis. Reason being, the experimental group of patients who received surgical stents to help prevent strokes actually experienced a greater incidence of stroke: 14.7 percent of patients with a brain stent had a stroke within the first 30 days of the study, while only 5.3 percent of the control group did.

All 451 patients who participated in the study shared the same high risk for stroke: each had recently suffered a transient ischemic attack (TIA) or a stroke and had severe stenosis, meaning that each had a cranial artery that was 70 to 99 percent narrowed due to a build-up of plaque. So why were the patients who underwent surgery to keep their blood vessels open more prone to stroke than those in the control group? Both groups were treated with “aggressive medical management,” that is, that they received antiplatelet drugs like Plavix or aspirin and intensively managed risk factors like diabetes, high blood pressure and high cholesterol.

Did having to rely solely on lifestyle changes and medications better empower the patients in the control group to heal themselves? Did playing a more active role in their healing, as opposed to placing responsibility for their recovery in the hands of their physicians, help jump-start their bodies’ natural healing capacities?

Yes, according to mind-body medicine enthusiasts (especially proponents of psychoneuroimmunology), but there’s more to it. Safely inserting a stent into a brain artery is much more difficult than inflating it within a coronary artery: the former procedure carries a higher risk of injury due to bleeding and the surgeon must thread the catheter a further distance –  all the way up from the groin area to the head region.

Yet patients have undergone brain stenting procedures since 2005, when the FDA approved brain stents for high risk patients (such as the ones in this study), despite lack of studies proving the safety and efficacy of such stents. Why did the FDA make a “humanitarian exemption” for such a risky procedure? Based on the success rate of coronary artery stenting, which is the best way to improve blood flow to the heart and preserve heart muscle during a heart attack, it seemed reasonable to think that brain stents would similarly help prevent stroke and preserve brain tissue.

One benefit of the study’s outcome, said neurologists, was that the relative harm of brain stenting was discovered before the procedure became standard medical practice. On a brighter note, the study also highlighted the power in aggressively make beneficial lifestyle changes and taking personal responsibility for health.

Stenting vs. Risk Factor Management with Narrowed Coronary Arteries

Without a doubt, stenting a patient’s coronary artery can save his or her life during a heart attack. Along with angioplasty (inserting a catheter into a patient’s blocked coronary artery and inflating a tiny balloon into the artery to open it and restore blood flow to the heart), stenting “fixes” the immediate problem of narrowed arteries.

Relying on a stent as the end-all-be-all cure is not the best way to protect against future cardiac events, though, as stenting does nothing to address the underlying causes of arterial stenosis and may result in the need for additional stents. Along with anticoagulant and other drug therapies, modifying lifestyle habits which contribute to overall arterial narrowing is a much better long-term strategy for improving and maintaining cardiovascular health.

Strokes and Heart Attacks: Risk Factor Management

Managing risk factors for stroke and heart attack, such as high blood pressure, diabetes and high cholesterol (too much small particle LDL, really) is a matter of making lifestyle changes, which could require a complete overhaul in the way you live. The key is reducing inflammation in the body, and here are some techniques for doing so:

You Are What You Eat

To help prevent or manage diabetes, as well as keep blood pressure and cholesterol at healthy levels, stick to eating non-Inflammatory Foods.

Generally, you want to avoid eating foods which generate inflammatory responses in your body, choosing instead foods which are non-inflammatory or even help fight inflammation.

Here are some basic tips for anti-inflammatory eating that also promotes healthy cholesterol, blood pressure and insulin levels:

Supplementation

In addition to eating high quality, nutritious food, you can get the nutrients you need to prevent inflammation and keep cholesterol and blood pressure at healthy levels by taking nutritional supplements. Take a quality multivitamin with lots of antioxidants that help prevent free radical onslaught in blood vessels. For cholesterol control, other helpful supplements include niacin, vitamin E, L-carnitine and pantethine, as well as coenzyme Q10, fish oil and garlic, which are also great for blood pressure management. Hawthorne, calcium and magnesium supplements can also help you keep your blood pressure low.

Get Moving!

Twenty to sixty minutes per day of moderate exercise is a staple of health maintenance. Exercise is not only an effective strategy for managing weight, preventing diabetes and reducing blood pressure and cholesterol levels; it also helps lower stress hormone levels, and even helps keep the blues away. Walking, dancing, playing non-competitive sports and swimming are just some examples of lower-impact exercise that won’t stress the joints or the heart. Remember not to engage in strenuous exercise, as it can create excess free radical activity in the body and thus contribute to inflammation.

Take it Easy!

Stress can be a killer, leading to high blood pressure, disease and even heart attacks. Learning not to let psycho-emotional stress get the better of you is one of the best lifestyle choices you can make to prepare yourself for unforeseen, and potentially stressful, circumstances. Regularly practicing mind-body therapies like yoga, meditation or even just deep breathing can help you train yourself to react more healthfully to stressors.

Engaging in the act of “play” – with your children (or grandchildren), pets, friends or partner can help alleviate stress, as can laughing or even crying. Massage and acupuncture are beneficial for releasing tension in the body caused by stress. For some, spirituality may come into play… belief in a higher power, whatever it may be, can help lift what seems like global weight on your shoulders.

Touch Ground

Grounding is also wonderful means of assuaging the physiological effects of stress: attuning to the earth’s natural electromagnetic energy helps generate a relaxation response and balance the autonomic nervous system. Grounding also helps keep blood thin, thus may reduce risk of blood clots which can cause heart attacks or strokes.

Ditch the Ciggies

Quit smoking… no ifs, ands or butts.

Love More…

Knowledge is power – often your best defense. Remember, though, what you know doesn’t mean much unless you apply it. Visit our blood pressure section to learn moreabout achieving and maintaining healthy blood pressure levels.

References / Additional Resources:

© 2011 HeartMD Institute. All rights reserved.

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